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Bioinformatics Advance Access originally published online on July 14, 2005
Bioinformatics 2005 21(17):3572-3574; doi:10.1093/bioinformatics/bti556
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© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

MAVisto: a tool for the exploration of network motifs

Falk Schreiber and Henning Schwöbbermeyer *

Leibniz Institute of Plant Genetics and Crop Plant Research 06466 Gatersleben, Germany

*To whom correspondence should be addressed.

Summary: MAVisto is a tool for the exploration of motifs in biological networks. It provides a flexible motif search algorithm and different views for the analysis and visualization of network motifs. These views help to explore interesting motifs: the frequency of motif occurrences can be compared with randomized networks, a list of motifs along with information about structure and number of occurrences depending on the reuse of network elements shows potentially interesting motifs, a motif fingerprint reveals the overall distribution of motifs of a given size and the distribution of a particular motif in the network can be visualized using an advanced layout algorithm.

Availability: MAVisto is platform independent and available free of charge as a Java webstart application at http://mavisto.ipk-gatersleben.de/

Contact: schwoebb{at}ipk-gatersleben.de

Supplementary information: Can be found at http://mavisto.ipk-gatersleben.de/

Received on June 10, 2005; revised on June 26, 2005; accepted on June 26, 2005

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