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Bioinformatics Advance Access originally published online on June 30, 2005
Bioinformatics 2005 21(17):3580-3581; doi:10.1093/bioinformatics/bti560
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© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

TO-GO: a Java-based Gene Ontology navigation environment

Ungsik Yu 1,*, Yoon Jeong Choi 1, Jung Kyoon Choi 1 and Sangsoo Kim 2

1National Genome Information Center, KRIBB Oun 52, Yusong, Daejeon 305-333, Korea
2Department of Bioinformatics and Life Science, Soongsil University Seoul, Korea

*To whom correspondence should be addressed.

Summary: TO-GO is a Gene Ontology (GO) navigation tool, which is implemented as a Java application. After the initial data downloading, the GO term tree can be interactively navigated without further network transfer. Local annotation can be incorporated. It supports querying by GO terms or associated gene product information, displaying the result as a table or a sub-tree. The result from the search for a set of external database accessions includes the number of gene products associated with each node, inclusive of sub-nodes. Search results can be further processed by set operations and these set operations can be quite useful for expression profile data analysis. A copy/paste function is also implemented in order to facilitate data exchange between applications.

Availability: TO-GO is freely available at http://www.ngic.re.kr/togo/index.html

Contact: ungsik{at}kribb.re.kr


Received on August 3, 2004; revised on May 31, 2005; accepted on June 27, 2005

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