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Bioinformatics Advance Access originally published online on August 4, 2005
Bioinformatics 2005 21(18):3674-3676; doi:10.1093/bioinformatics/bti610
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© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research

Ana Conesa 1,*,{dagger}, Stefan Götz 2,{dagger}, Juan Miguel García-Gómez 2, Javier Terol 1, Manuel Talón 1 and Montserrat Robles 2

1Centro de Genómica, Instituto Valenciano de Investigaciones Agrarias Moncada, Valencia, Spain
2BET-ITACA, Universidad Politécnica de Valencia Valencia, Spain

*To whom correspondence should be addressed.

Summary: We present here Blast2GO (B2G), a research tool designed with the main purpose of enabling Gene Ontology (GO) based data mining on sequence data for which no GO annotation is yet available. B2G joints in one application GO annotation based on similarity searches with statistical analysis and highlighted visualization on directed acyclic graphs. This tool offers a suitable platform for functional genomics research in non-model species. B2G is an intuitive and interactive desktop application that allows monitoring and comprehension of the whole annotation and analysis process.

Availability: Blast2GO is freely available via Java Web Start at http://www.blast2go.de

Supplementary material: http://www.blast2go.de -> Evaluation

Contact: aconesa{at}ivia.es; stefang{at}fis.upv.es

Received on June 27, 2005; revised on July 28, 2005; accepted on July 29, 2005

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