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Bioinformatics Advance Access originally published online on August 2, 2005
Bioinformatics 2005 21(18):3683-3685; doi:10.1093/bioinformatics/bti605
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© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis

Claire L. Wilson and Crispin J. Miller *

Paterson Institute for Cancer Research Wilmslow Road, Manchester M20 4BX, UK

*To whom correspondence should be addressed.

Summary: Quality Control is a fundamental aspect of successful microarray data analysis. Simpleaffy is a BioConductor package that provides access to a variety of QC metrics for assessing the quality of RNA samples and of the intermediate stages of sample preparation and hybridization. Simpleaffy also offers fast implementations of popular algorithms for generating expression summaries and detection calls.

Availability: Simpleaffy can be downloaded from http://www.bioconductor.org

Contact: cmiller{at}picr.man.ac.uk

Supplementary information: Additional information can be found on the supplementary website located at http://bioinformatics.picr.man.ac.uk

Received on June 9, 2005; revised on July 18, 2005; accepted on July 28, 2005

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