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Bioinformatics Advance Access originally published online on August 25, 2005
Bioinformatics 2005 21(20):3935-3937; doi:10.1093/bioinformatics/bti643
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© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oxfordjournals.org

PAWE-3D: visualizing power for association with error in case–control genetic studies of complex traits

Derek Gordon 1,*, Chad Haynes 1, Jon Blumenfeld 2,3 and Stephen J. Finch 4

1Laboratory of Statistical Genetics, Rockefeller University 1230 York Avenue, New York, NY 10021, USA
2The Rogosin Institute 505 East 70th Street, New York, NY 10021, USA
3Weill Medical College of Cornell University 1300 York Avenue, New York, NY 10021, USA
4Department of Applied Mathematics and Statistics, Stony Brook University Stony Brook, NY 11794, USA

*To whom correspondence should be addressed.

Summary: A website that plots power and sample size calculations over a range of up to eight parameters (including diagnostic misclassification error parameters) for two commonly used statistical tests of genetic association, the linear trend test and the genotypic test of association.

Availability: This method is made available via the website http://linkage.rockefeller.edu/pawe3d/

Contact: pawe3d{at}linkage.rockefeller.edu

Received on May 31, 2005; revised on August 18, 2005; accepted on August 22, 2005

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