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Bioinformatics Advance Access originally published online on August 30, 2005
Bioinformatics 2005 21(20):3938-3939; doi:10.1093/bioinformatics/bti649
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© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oxfordjournals.org

HAPLOT: a graphical comparison of haplotype blocks, tagSNP sets and SNP variation for multiple populations

Sheng Gu *, Andrew J. Pakstis and Kenneth K. Kidd

Department of Genetics, Yale University School of Medicine New Haven, USA

*To whom correspondence should be addressed.

Summary: Understanding of human variation relevant to association studies can benefit from population comparison, especially comparing populations in the same geographical region. Variations in linkage disequilibrium patterns, in tagSNP sets, and in SNP heterozygosities among populations can be used to infer the evolutionary pattern. We present here a win32 system based Perl/Tk application for visual comparisons of these variations in different populations.

Availability: The application package is available at http://info.med.yale.edu/genetics/kkidd/programs.html

Contact: sheng.gu{at}yale.edu


Received on July 13, 2005; revised on August 24, 2005; accepted on August 25, 2005

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