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Bioinformatics Advance Access originally published online on September 27, 2005
Bioinformatics 2005 21(23):4309-4311; doi:10.1093/bioinformatics/bti689
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© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oxfordjournals.org

HapSim: a simulation tool for generating haplotype data with pre-specified allele frequencies and LD coefficients

Giovanni Montana

Department of Mathematics, Imperial College London, UK

We have developed a simulation tool HapSim for the generation of haplotype data. The simulated haplotypes are such that their allele frequencies and linkage disequilibrium coefficients match exactly those estimated in a real sample.

Availability: The program is available as an R package and can be downloaded from http://cran.r-project.org/

Contact: g.montana{at}imperial.ac.uk

Received on August 1, 2005; revised on September 21, 2005; accepted on September 22, 2005

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