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Bioinformatics Advance Access originally published online on September 9, 2004
Bioinformatics 2005 21(3):408-409; doi:10.1093/bioinformatics/bti017
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Bioinformatics vol. 21 issue 3 © Oxford University Press 2005; all rights reserved.

Human–Mouse Gene Searcher: a tool to assist discovery of malformation-associated genes by using phenotype databases

Ian Bradford 1,*, Robin Winter 1,{dagger}, Carl Evans 2 and Jonathan Bard 3

1 Institute of Child Health 30 Guilford Street, London WC1N 1EH, UK
2 School of Computing Science, Middlesex University London, UK
3 Bioinformatics, Medical School, University of Edinburgh London, EH8 9XD, UK

*To whom correspondence should be addressed.

An open-access World Wide Web application has been developed which enables the cross-linking of anatomical data on the phenotypic manifestations of human and mouse malformation syndromes to data on gene function and/or expression patterns in the mouse GXD database. Ultimately, the system has been designed to assist biologists in the process of discovering hitherto unidentified malformation genes. More specifically, it facilitates search from the phenotypic level.

Availability: The application and further information is available at http://genetics.ich.ucl.ac.uk/linksearchtool

Contact: i.bradford{at}ich.ucl.ac.uk


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