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Bioinformatics Advance Access originally published online on October 28, 2004
Bioinformatics 2005 21(6):829-831; doi:10.1093/bioinformatics/bti106
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© The Author 2004. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

GOChase: correcting errors from Gene Ontology-based annotations for gene products

Yu Rang Park 1, Chan Hee Park 1 and Ju Han Kim 1,2,*

1Seoul National University Biomedical Informatics (SNUBI), Seoul National University College of Medicine Seoul 110–799, Korea
2Human Genome Research Institute, Seoul National University College of Medicine Seoul 110–799, Korea

*To whom correspondence should be addressed.

Summary: The Gene Ontology (GO) is a controlled biological vocabulary that provides three structured networks of terms to describe biological processes, cellular components and molecular functions. Many databases of gene products are annotated using the GO vocabularies. We found that some GO-updating operations are not easily traceable by the current biological databases and GO browsers. Consequently, numerous annotation errors arise and are propagated throughout biological databases and GO-based high-level analyses. GOChase is a set of web-based utilities to detect and correct the errors in GO-based annotations.

Availability: http://www.snubi.org/software/GOChase/

Contact: juhan{at}snu.ac.kr


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