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Bioinformatics Advance Access originally published online on December 10, 2004
Bioinformatics 2005 21(8):1699-1700; doi:10.1093/bioinformatics/bti194
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© The Author 2004. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

HESAS: HERVs Expression and Structure Analysis System

Tae-Hyung Kim 1, Yeo-Jin Jeon 1, Woo-Yeon Kim 1 and Heui-Soo Kim 1,2,*

1PBBRC, Interdisciplinary Research Program of Bioinformatics, College of Natural Sciences, Pusan National University Busan 609–735, Korea
2Division of Biological Sciences, College of Natural Sciences, Pusan National University Busan 609–735, Korea

*To whom correspondence should be addressed.

Summary: HESAS (HERVs Expression and Structure Analysis System) database was developed to understand the human endogenous retroviruses (HERVs) that have an effect on the expression of human functional genes. The database products are generated by the exon-based expressed sequence tag clustering and reconstructing of partial HERV structures that result from various mutations during primate evolution. The expression types were classified according to the existence of splicing, transcriptional start and polyadenylation signal sites. The database currently contains HERV information on 26 981 human genes of exon–intron structure. The HERV elements were inserted into 17 317 of these genes and linked to expression with 898 genes.

Availability: http://www.primate.or.kr/HESAS

Contact: khs307{at}pusan.ac.kr


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