Bioinformatics Advance Access originally published online on December 7, 2004
Bioinformatics 2005 21(8):1719-1720; doi:10.1093/bioinformatics/bti203
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Porter: a new, accurate server for protein secondary structure prediction
1Computer Science Department, University College Dublin Belfield, Dublin 4, Ireland
2Genetics Department, Trinity College Dublin Dublin 2, Ireland
*To whom correspondence should be addressed.
Summary: Porter is a new system for protein secondary structure prediction in three classes. Porter relies on bidirectional recurrent neural networks with shortcut connections, accurate coding of input profiles obtained from multiple sequence alignments, second stage filtering by recurrent neural networks, incorporation of long range information and large-scale ensembles of predictors. Porter's accuracy, tested by rigorous 5-fold cross-validation on a large set of proteins, exceeds 79%, significantly above a copy of the state-of-the-art SSpro server, better than any system published to date.
Availability: Porter is available as a public web server at http://distill.ucd.ie/porter/
Contact: gianluca.pollastri{at}ucd.ie
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
S. Montgomerie, J. A. Cruz, S. Shrivastava, D. Arndt, M. Berjanskii, and D. S. Wishart PROTEUS2: a web server for comprehensive protein structure prediction and structure-based annotation Nucleic Acids Res., July 1, 2008; 36(suppl_2): W202 - W209. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Orlowski and J. M. Bujnicki Structural and evolutionary classification of Type II restriction enzymes based on theoretical and experimental analyses Nucleic Acids Res., June 1, 2008; 36(11): 3552 - 3569. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. M. Walraven, J. O. Trent, and D. W. Hein Computational and Experimental Analyses of Mammalian Arylamine N-Acetyltransferase Structure and Function Drug Metab. Dispos., June 1, 2007; 35(6): 1001 - 1007. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Darewicz, J. Dziuba, and P. Minkiewicz Computational Characterisation and Identification of Peptides for in silico Detection of Potentially Celiac-Toxic Proteins Food Science and Technology International, April 1, 2007; 13(2): 125 - 133. [Abstract] [PDF] |
||||
![]() |
A. Vullo, O. Bortolami, G. Pollastri, and S. C. E. Tosatto Spritz: a server for the prediction of intrinsically disordered regions in protein sequences using kernel machines. Nucleic Acids Res., July 1, 2006; 34(Web Server issue): W164 - W168. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Hiraoka, A. Abe, and J. A. Shayman Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues J. Lipid Res., November 1, 2005; 46(11): 2441 - 2447. [Abstract] [Full Text] [PDF] |
||||



