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Bioinformatics Advance Access originally published online on January 27, 2005
Bioinformatics 2005 21(9):2108-2109; doi:10.1093/bioinformatics/bti289
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Published by Oxford University Press 2005.

ProfDist: a tool for the construction of large phylogenetic trees based on profile distances

Joachim Friedrich 1,2, Thomas Dandekar 1, Matthias Wolf 1 and Tobias Müller 1,*

1Department of Bioinformatics, Biocenter, University of Würzburg Am Hubland, D-97074 Würzburg, Germany
2Department of Theoretical Computer Science, RWTH Aachen Ahornstrasse 55, D-52074 Aachen, Germany

*To whom correspondence should be addressed

Summary: ProfDist is a user-friendly software package using the profile-neighbor-joining method (PNJ) in inferring phylogenies based on profile distances on DNA or RNA sequences. It is a tool for reconstructing and visualizing large phylogenetic trees providing new and standard features with a special focus on time efficency, robustness and accuracy.

Availability: A Windows version of ProfDist comes with a graphical user interface and is freely available at http://profdist.bioapps.biozentrum.uni-wuerzburg.de

Contact: tobias.mueller{at}biozentrum.uni-wuerzburg.de


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[Abstract] [Full Text] [PDF]


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