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Bioinformatics Advance Access originally published online on March 30, 2006
Bioinformatics 2006 22(12):1534-1535; doi:10.1093/bioinformatics/btl113
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

GenRGenS: software for generating random genomic sequences and structures

Yann Ponty 1, Michel Termier 2 and Alain Denise 1,*

1 LRI, UMR CNRS 8623, Université Paris-Sud 11 F91405 Orsay cedex, France
2 IGM, UMR CNRS 8621, Université Paris-Sud 11 F91405 Orsay cedex, France

*To whom correspondence should be addressed.

Summary: GenRGenS is a software tool dedicated to randomly generating genomic sequences and structures. It handles several classes of models useful for sequence analysis, such as Markov chains, hidden Markov models, weighted context-free grammars, regular expressions and PROSITE expressions. GenRGenS is the only program that can handle weighted context-free grammars, thus allowing the user to model and to generate structured objects (such as RNA secondary structures) of any given desired size. GenRGenS also allows the user to combine several of these different models at the same time.

Availability: Source and executable files of GenRGenS (in Java) and the complete user's manual are freely available at http://www.lri.fr/bio/GenRGenS

Contact: dev.GenRGenS{at}lri.fr


Received on February 21, 2006; revised on March 13, 2006; accepted on March 21, 2006

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