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Bioinformatics Advance Access originally published online on May 8, 2006
Bioinformatics 2006 22(14):1786-1787; doi:10.1093/bioinformatics/btl179
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

HoSeqI: automated homologous sequence identification in gene family databases

Anne-Muriel Arigon *, Guy Perrière and Manolo Gouy

Laboratoire de Biométrie et Biologie Évolutive, UMR CNRS 5558, Université Claude-Bernard Lyon 1, 43 boulevard du 11 Novembre 1918 69622 Villeurbanne Cedex, France

*To whom correspondence should be addressed.

Summary: We present a web service allowing to automatically assign sequences to homologous gene families from a set of databases. After identification of the most similar gene family to the query sequence, this sequence is added to the whole alignment and the phylogenetic tree of the family is rebuilt. Thus, the phylogenetic position of the query sequence in its gene family can be easily identified.

Availability: http://pbil.univ-lyon1.fr/software/HoSeqI/

Contact: arigon{at}biomserv.univ-lyon1.fr

Supplementary Information: Supplementary Data are available at Bioinformatics online.

Received on February 17, 2006; revised on April 19, 2006; accepted on May 3, 2006

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