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Bioinformatics Advance Access originally published online on May 3, 2006
Bioinformatics 2006 22(14):1790-1791; doi:10.1093/bioinformatics/btl164
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

TopoICE-R: 3D visualization modeling the topology of DNA recombination

Isabel K. Darcy 1,* and Robert G. Scharein 2

1 Department of Mathematics, University of Iowa Iowa City, IA 52242, USA
2 Hypnagogic Software Vancouver, BC, Canada

*To whom correspondence should be addressed.

TopoICE-R is a three-dimensional visualization and manipulation software for solving 2-string tangle equations and can be used to model the topology of DNA bound by proteins such as recombinases and topoisomerases.

Availability: This software, manual and example files are available at www.knotplot.com/download for Linux, Windows and Mac.

Contact: idarcy{at}math.uiowa.edu


Received on October 13, 2005; revised on March 26, 2006; accepted on April 26, 2006

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Nucleic Acids ResHome page
I. K. Darcy, R. G. Scharein, and A. Stasiak
3D visualization software to analyze topological outcomes of topoisomerase reactions
Nucleic Acids Res., June 1, 2008; 36(11): 3515 - 3521.
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