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Bioinformatics Advance Access originally published online on May 18, 2006
Bioinformatics 2006 22(15):1924-1925; doi:10.1093/bioinformatics/btl196
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Comparative gene marker selection suite

Joshua Gould *, Gad Getz , Stefano Monti , Michael Reich and Jill P. Mesirov

Broad Institute of MIT and Harvard Cambridge, MA 02142, USA

*To whom correspondence should be addressed.

Motivation: An important step in analyzing expression profiles from microarray data is to identify genes that can discriminate between distinct classes of samples. Many statistical approaches for assigning significance values to genes have been developed. The Comparative Marker Selection suite consists of three modules that allow users to apply and compare different methods of computing significance for each marker gene, a viewer to assess the results, and a tool to create derivative datasets and marker lists based on user-defined significance criteria.

Availability: The Comparative Marker Selection application suite is freely available as a GenePattern module. The GenePattern analysis environment is freely available at http://www.broad.mit.edu/genepattern

Contact: jgould{at}broad.mit.edu

Received on March 13, 2006; revised on April 21, 2006; accepted on May 15, 2006

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