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Bioinformatics Advance Access originally published online on July 4, 2006
Bioinformatics 2006 22(17):2180-2182; doi:10.1093/bioinformatics/btl358
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

ZooDDD: a cross-species database for digital differential display analysis

Yun-Ching Chen 1,{dagger}, Chung-Der Hsiao 2,{dagger}, Wen-Dar Lin 1, Chung-Ming Hu 1, Pung-Pung Hwang 2,* and Jan-Ming Ho 1

1 Institute of Information Science, Academia Sinica NanKang 115, Taipei, Taiwan, Republic of China
2 Institute of Cellular and Organismic Biology, Academia Sinica NanKang 115, Taipei, Taiwan, Republic of China

*To whom correspondence should be addressed.

Summary: In this article, we combined EST information from the UniGene database and orthologous relationships from the Ensembl database to construct a ZooDDD database. The primary function of ZooDDD is to mine evolutionary conserved, highly expressed, tissue-specific orthologues in model animals. The candidate genes of interest derived from the ZooDDD database will provide biologists with a good step for comparing the expression, functions and evolution of animal genomes.

Availability: http://bio301.iis.sinica.edu.tw/~ZooDDDNew/main.php

Contact: cyc{at}iis.sinica.edu.tw, pphwang{at}gate.sinica.edu.tw, hoho{at}iis.sinica.edu.tw

Received on March 12, 2006; revised on May 26, 2006; accepted on June 24, 2006

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