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Bioinformatics Advance Access originally published online on July 14, 2006
Bioinformatics 2006 22(18):2315-2316; doi:10.1093/bioinformatics/btl385
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

OrderedList—a bioconductor package for detecting similarity in ordered gene lists

Claudio Lottaz 1,*, Xinan Yang 1,2, Stefanie Scheid 1 and Rainer Spang 1

1 Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics Ihnestrasse 63-73, D-14195 Berlin, Germany
2 State Key Laboratory of Bioelectronics, Southeast University 210096 Nanjing, People's Repuplic of China

*To whom correspondence should be addressed.

Summary: OrderedList is a Bioconductor compliant package for meta-analysis based on ordered gene lists like those resulting from differential gene expression analysis. Our package quantifies the similarity between gene lists. The significance of the similarity score is estimated from random scores computed on perturbed data. OrderedList illustrates list similarity in intuitive plots and determines the score-driving genes for further analysis.

Availability: http://www.bioconductor.org

Contact: claudio.lottaz{at}molgen.mpg.de

Supplementary information: Please visit our webpage on http://compdiag.molgen.mpg.de/software

Received on April 28, 2006; revised on June 26, 2006; accepted on July 6, 2006

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