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Bioinformatics Advance Access originally published online on July 31, 2006
Bioinformatics 2006 22(20):2577-2579; doi:10.1093/bioinformatics/btl422
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Sebida: a database for the functional and evolutionary analysis of genes with sex-biased expression

Florian Gnad 1,* and John Parsch 2

1 Max Planck Institute of Biochemistry, Am Klopferspitz 18 82152 Martinsried, Germany
2 Department of Biology, University of Munich (LMU) Grosshaderner Strasse 2, 82152 Planegg-Martinsried, Germany

*To whom correspondence should be addressed.

Summary: We describe Sebida, a database of genes with sex-biased expression. The database integrates results from multiple, independent microarray studies comparing male and female gene expression in Drosophila melanogaster, Drosophila simulans and Anopheles gambiae. Sebida uses standard nomenclature, which allows individual genes to be compared across different microarray platforms and to be queried by gene name, symbol, or annotation number. In addition to ratios of male/female expression for each gene, Sebida also contains information useful for evolutionary studies, such as local recombination rate, degree of codon bias and interspecific divergence at synonymous and non-synonymous sites.

Availability: Sebida can be accessed at http://www.sebida.de

Contact: gnad{at}biochem.mpg.de

Received on April 26, 2006; revised on July 12, 2006; accepted on July 28, 2006

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