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Bioinformatics Advance Access originally published online on March 16, 2006
Bioinformatics 2006 22(9):1150-1151; doi:10.1093/bioinformatics/btl091
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

WebCell: a web-based environment for kinetic modeling and dynamic simulation of cellular networks

Dong-Yup Lee 1,2,{dagger},{ddagger}, Choamun Yun 1,2,{dagger}, Ayoun Cho 1, Bo Kyeng Hou 2, Sunwon Park 1 and Sang Yup Lee 1,2,3,*

1 Department of Chemical and Biomolecular Engineering, Metabolic and Biomolecular Engineering National Research Laboratory 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Korea
2 Bioinformatics Research Center, Korea Advanced Institute of Science and Technology 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Korea
3 Department of BioSystems, Korea Advanced Institute of Science and Technology 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Korea

*To whom correspondence should be addressed.

Summary: WebCell is a web-based environment for managing quantitative and qualitative information on cellular networks and for interactively exploring their steady-state and dynamic behaviors in response to systemic perturbations. It is designed as a user-friendly web interface, allowing users to efficiently construct, visualize, analyze and store reaction network models, thereby facilitating kinetic modeling and in silico simulation of biological systems of interest. A collected model library is also available to provide comprehensive implications for cellular dynamics of the published models.

Availability: WebCell is accessible at http://webcell.kaist.ac.kr or http://webcell.org.

Contact: leesy{at}kaist.ac.kr

Received on January 3, 2006; revised on March 7, 2006; accepted on March 7, 2006

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