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Bioinformatics Advance Access originally published online on May 7, 2007
Bioinformatics 2007 23(12):1553-1555; doi:10.1093/bioinformatics/btm128
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© The Author 2007. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

SQUINT: a multiple alignment program and editor

Matthew G. Goode and Allen G. Rodrigo *

Bioinformatics Institute, Private Bag 92019, University of Auckland, Auckland, New Zealand

*To whom correspondence should be addressed.


   Abstract

Summary: SQUINT is a sequence alignment tool, and combines both automated progressive sequence alignment with facilities for manual editing. The program imports nucleotide or amino acid sequence multiple alignment files in standard formats, and permits users to view two translations of the same multiple alignment simultaneously. Edits in one view are instantaneously reflected in the other, and the scoring cost of the changes are shown in real-time. Progressive multiple alignments, using a variety of alignment parameters, can be performed on any block of sequences, including blocks embedded in the existing alignment.

Availability: The software is freely available for download at http://www.cebl.auckland.ac.nz

Contact: a.rodrigo{at}auckland.ac.nz

Associate Editor: Keith Crandall


Received on December 6, 2006; revised on February 8, 2007; accepted on March 26, 2007

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