Bioinformatics Advance Access originally published online on June 28, 2007
Bioinformatics 2007 23(17):2337-2338; doi:10.1093/bioinformatics/btm330
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POODLE-S: web application for predicting protein disorder by using physicochemical features and reduced amino acid set of a position-specific scoring matrix
1Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), 2-42 Aomi, Koto-ku, Tokyo 135-0064 and 2PharmaDesign, Inc., 2-19-8 Hatchobori, Chuo-ku, Tokyo 104-0032, Japan
*To whom correspondence should be addressed.
| Abstract |
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Summary: Protein disorder is characterized by a lack of a stable 3D structure, and is considered to be involved in a number of important protein functions such as regulatory and signalling events. We developed a web application, the POODLE-S, which predicts the disordered region from amino acid sequences by using physicochemical features and reduced amino acid set of a position-specific scoring matrix.
Availability: POODLE-S is available from http://mbs.cbrc.jp/poodle/poodle-s.html and can be used by both academic and commercial users.
Contact: poodle{at}cbrc.jp
Associate Editor: Anna Tramontano
Received on April 4, 2007; revised on May 2, 2007; accepted on June 16, 2007
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