Bioinformatics Advance Access originally published online on October 31, 2007
Bioinformatics 2007 23(22):3088-3090; doi:10.1093/bioinformatics/btm512
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CONSORF: a consensus prediction system for prokaryotic coding sequences
1KOBIC (Korean BioInformation Center), KRIBB, Daejeon 305-806 and 2Soongsil University, 1-1 Sangdo-dong, Dongjak-gu, Seoul 156-743, Korea
*To whom correspondence should be addressed.
| Abstract |
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Summary: CONSORF is a fully automatic high-accuracy identification system that provides consensus prokaryotic CDS information. It first predicts the CDSs supported by consensus alignments. The alignments are derived from multiple genome-to-proteome comparisons with other prokaryotes using the FASTX program. Then, it fills the empty genomic regions with the CDSs supported by consensus ab initio predictions. From those consensus results, CONSORF provides prediction reliability scores, predicted frame-shifts, alternative start sites and best pair-wise match information against other prokaryotes. These results are easily accessed from a website.
Availability: The regularly updated CDS predictions of prokaryotic genomes as well as the source code are freely accessible through http://consorf.kobic.re.kr and http://orfome.org.
Contact: j{at}bio.cc, jong{at}kribb.re.kr or sskimb{at}ssu.ac.kr
Supplementary information: The detailed methods and evaluation results can be found at http://consorf.kobic.re.kr/supplementary/.
Associate Editor: Alfonso Valencia
Received on May 18, 2007; revised on September 20, 2007; accepted on October 8, 2007