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Bioinformatics Advance Access originally published online on September 25, 2007
Bioinformatics 2007 23(22):3103-3104; doi:10.1093/bioinformatics/btm462
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© The Author 2007. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

CellMontage: similar expression profile search server

Wataru Fujibuchi 1, Larisa Kiseleva 1, Takeaki Taniguchi 2, Hajime Harada 1 and Paul Horton 1,*

1Computational Biology Research Center, AIST Waterfront Bio-IT Research Building, 2-42 Aomi Koto-ku, Tokyo 135-0064 and 2Mitsubishi Research Institute, Inc., 3-6, Otemachi 2-chome Chiyoda-ku, Tokyo 100-8141, Japan

*To whom correspondence should be addressed.


  Abstract

Summary: The establishment and rapid expansion of microarray databases has created a need for new search tools. Here we present CellMontage, the first server for expression profile similarity search over a large database—69 000 microarray experiments derived from NCBI's; GEO site. CellMontage provides a novel, content-based search engine for accessing gene expression data. Microarray experiments with similar overall expression to a user-provided expression profile (e.g. microarray experiment) are computed and displayed—usually within 20 s. The core search engine software is downloadable from the site.

Availability: http://cellmontage.cbrc.jp/

Contact: horton-p{at}aist.go.jp

Supplementary information: http://cellmontage.cbrc.jp/supplementary/

Associate Editor: Martin Bishop

Received on July 17, 2007; revised on August 17, 2007; accepted on September 6, 2007

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