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Bioinformatics Advance Access originally published online on December 4, 2006
Bioinformatics 2007 23(4):498-499; doi:10.1093/bioinformatics/btl618
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

AutoGRAPH: an interactive web server for automating and visualizing comparative genome maps

Thomas Derrien , Catherine André , Francis Galibert and Christophe Hitte *

CNRS UMR6061 Génétique et Développement, Université de Rennes1 IFR140, 2 Av du Pr. Léon Bernard, CS 34317, 35043, France

*To whom correspondence should be addressed.


  Abstract

AutoGRAPH is an interactive web server for automatic multi-species comparative genomics analyses based on personal datasets or pre-inserted public datasets. This program automatically identifies conserved segments (CS) and breakpoint regions, assesses the conservation of marker/gene order between organisms, constructs synteny maps for two to three species and generates high-quality, interactive displays facilitating the identification of chromosomal rearrangements. AutoGRAPH can also be used for the integration and comparison of several types of genomic resources (meiotic maps, radiation hybrid maps and genome sequences) for a single species, making AutoGRAPH a versatile tool for comparative genomics analysis.

Availability: http://genoweb.univ-rennes1.fr/tom_dog/AutoGRAPH/

Contact: hitte{at}univ-rennes1.fr

Supplementary information: A description of the algorithm and additional information are available at http://genoweb.univ-rennes1.fr/tom_dog/AutoGRAPH/Tutorial.php

Associate Editor: Alfonso Valencia

Received on September 20, 2006; revised on November 29, 2006; accepted on November 29, 2006

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