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Bioinformatics Advance Access originally published online on April 14, 2008
Bioinformatics 2008 24(11):1406-1407; doi:10.1093/bioinformatics/btn136
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© The Author 2008. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Analysing georeferenced population genetics data with Geneland: a new algorithm to deal with null alleles and a friendly graphical user interface

Gilles Guillot 1,2,*, Filipe Santos 3 and Arnaud Estoup 3

1Centre for Ecological and Evolutionary Synthesis, Department of Biology, University of Oslo, P.O Box 1066 Blindern, 0316 Oslo, Norway, 2Applied Mathematics Department, INRA, Paris and 3Centre de Biologie et de Gestion des Populations, INRA / IRD / CIRAD / Montpellier SupAgro, Campus international de Baillarguet, CS 30016, F-34988 Montferrier-sur-Lez cedex, France

*To whom correspondence should be addressed.


  Abstract

Summary: We introduce a new algorithm to account for the presence of null alleles in inferences of populations clusters from individual multilocus genetic data. We show by simulations that the presence of null alleles can affect the accuracy of inferences if not properly accounted for and that our algorithm improve signficantly their accuracy.

Availability: This new algorithm is implemented in the program Geneland. It is freely available under GNU public license as an R package on the Comprehensive R Archive Network. It now includes a fully clickable graphical interface. Informations on how to get the software are available on folk.uio.no/gillesg/Geneland.html

Contact: gilles.guillot{at}bio.uio.no

Supplementary information: Details on the simulation study are available from folk.uio.no/gillesg/BioInformatics_Geneland

Associate Editor: Martin Bishop

Received on March 27, 2008; revised on April 9, 2008; accepted on April 9, 2008

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G. Guillot
Inference of structure in subdivided populations at low levels of genetic differentiation--the correlated allele frequencies model revisited
Bioinformatics, October 1, 2008; 24(19): 2222 - 2228.
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