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Bioinformatics Advance Access originally published online on May 1, 2008
Bioinformatics 2008 24(13):1552-1553; doi:10.1093/bioinformatics/btn219
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© The Author 2008. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

quantiNemo: an individual-based program to simulate quantitative traits with explicit genetic architecture in a dynamic metapopulation

Samuel Neuenschwander 1,*, Frédéric Hospital 1,2, Frédéric Guillaume 3 and Jérôme Goudet 1

1Department of Ecology and Evolution, University of Lausanne, CH-1015 Lausanne, Switzerland, 2INRA, UMR Génétique et Diversité Animales, 78352 Jouy-en-Josas Cedex, France and 3Department of Zoology, University of British Columbia, Vancouver, B.C., V6T 1Z4, Canada

*To whom correspondence should be addressed.


  Abstract

Summary: quantiNemo is an individual-based, genetically explicit stochastic simulation program. It was developed to investigate the effects of selection, mutation, recombination and drift on quantitative traits with varying architectures in structured populations connected by migration and located in a heterogeneous habitat. quantiNemo is highly flexible at various levels: population, selection, trait(s) architecture, genetic map for QTL and/or markers, environment, demography, mating system, etc. quantiNemo is coded in C++ using an object-oriented approach and runs on any computer platform.

Availability: Executables for several platforms, user's manual, and source code are freely available under the GNU General Public License at http://www2.unil.ch/popgen/softwares/quantinemo

Contact: samuel.neuenschwander{at}unil.ch

Associate Editor: Martin Bishop

Received on March 15, 2008; revised on April 25, 2008; accepted on April 30, 2008

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