Bioinformatics Advance Access originally published online on February 25, 2009
Bioinformatics 2009 25(6):836-837; doi:10.1093/bioinformatics/btp069
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BISEN: Biochemical Simulation Environment
1BioModeling and Bioinformatics, BioMedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands, 2Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA and 3Lilly-Singapore Centre for Drug Discovery Pte Ltd, Singapore
*To whom correspondence should be addressed.
| Abstract |
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Summary: The Biochemical Simulation Environment (BISEN) is a suite of tools for generating equations and associated computer programs for simulating biochemical systems in the MATLAB® computing environment. This is the first package that can generate appropriate systems of differential equations for user-specified multi-compartment systems of enzymes and transporters accounting for detailed biochemical thermodynamics, rapid equilibria of multiple biochemical species and dynamic proton and metal ion buffering.
Availability: The software and a user manual (including several tutorial examples) are available at bbc.mcw.edu/BISEN.
Contact: dbeard{at}mcw.edu
Associate Editor: Alfonso Valencia
Received on November 24, 2008; revised on January 23, 2009; accepted on January 28, 2009