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© Oxford University Press

CLUSTAL V: improved software for multiple sequence alignment

Desmond G. Higgins , Alan J. Bleasby 1 and Rainer Fuchs

European Molecular Biology Laboratory Postfach 10.2209, 6900 Heidelberg, FRG
1Daresbury Laboratory Warrington WA4 4AD, UK

The CLUSTAL package of multiple sequence alignment programs has been completely rewritten and many new features added. The new software is a single program called CLUSTAL V, which is written in C and can be used on standard C compiler. The main new features are the ability to store and reuse old alignments and the ability to calculate phylogenetic trees after alignment. The program is simple to use, completely menu driven and on-line help is provided.


Received on August 5, 1991; accepted on August 23, 1991

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