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Bioinformatics Advance Access published online on February 12, 2004

Bioinformatics, doi:10.1093/bioinformatics/bth087
Bioinformatics © Oxford University Press 2004; all rights reserved
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Received July 10, 2003
Revised October 29, 2003
Accepted December 22, 2003

Applications note

NetAffx Gene Ontology Mining Tool: a visual approach for microarray data analysis

Jill Cheng 1*, Shaw Sun 1, Adam Tracy 1, Earl Hubbell 1, Joseph Morris 1, Venu Valmeekam 1, Andrew Kimbrough 1, Melissa S. Cline 1, Guoying Liu 1, Ron Shigeta 1, David Kulp 1, Michael A. Siani-Rose 1

1 Affymetrix Corporation, Bioinformatics, 6550 Vallejo Street, Suite 100, Emeryville, CA 94608, USA

* To whom correspondence should be addressed. E-mail: jill_cheng{at}affymetrix.com.


   Abstract

Summary: The NetAffx Gene Ontology (GO) Mining Tool is a web-based, interactive tool which permits traversal of the GO graph in the context of microarray data. It accepts a list of Affymetrix probe sets and renders a GO graph as a heat map colored according to significance measurements. The rendered graph is interactive, with nodes linked to public web sites, and to lists of the relevant probe sets. The GO Mining Tool provides visualization combining biological annotation with expression data, encompassing thousands of genes in one interactive view.

Availability: Go Mining Tool is freely available at http://www.affymetrix.com/analysis/query/go_analysis.affx.


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