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Bioinformatics Advance Access published online on April 15, 2004
Bioinformatics, doi:10.1093/bioinformatics/bth114
Bioinformatics © Oxford University Press 2004; all rights reserved
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Received July 18, 2003
Revised November 18, 2003
Accepted November 25, 2003

Article

PIN (proteins interacting in the nucleus) DB: a database of nuclear protein complexes from human and yeast

Phuong-Van Luc 1 Paul Tempst 1*

1 Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA

* To whom correspondence should be addressed. E-mail: p-tempst{at}mskcc.org.


  Abstract

Summary: PINdb is database of protein complexes purified from the nucleus of human and yeast cells. It is compiled from published literature and existing databases. Currently, PIN contains mostly protein complexes that may be involved in gene transcription. To facilitate comparative analyses and identification of protein complexes, the compositional information is integrated with standardized gene nomenclature, annotation, and protein sequence from public databases. PIN web interface provides a number of tools for: (1) comparison of protein complexes, (2) search for a protein complex by its published name or by a partial list of its components, and (3) browsing specific subsets or a functional classification of the complexes.

Availablity: http://pin.mskcc.org.


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