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Bioinformatics Advance Access published online on April 1, 2004
Bioinformatics, doi:10.1093/bioinformatics/bth224
Bioinformatics © Oxford University Press 2004; all rights reserved
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Received January 26, 2004
Accepted February 16, 2004

Applications note

PedSplit: pedigree management for stratified analysis

M. B. Lanktree 1*, L. VanderBeek 1, F. M. Macciardi 2, J. L. Kennedy 1

1 Neurogenetics Section, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, 250 College Street, Toronto M5T 1R8, Canada
2 Neurogenetics Section, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, 250 College Street, Toronto M5T 1R8, Canada; Department of Human Genetics, University of Milan, Italy

* To whom correspondence should be addressed. E-mail: Matthew_Lanktreep{at}camh.net.


  Abstract

Summary: PedSplit facilitates pedigree management for gene-gene interaction and sex specific tests for increased homogeneity within subgroups. PedSplit also provides a simple approach for calculating Haplotype Relative Risk (HRR) and generating internal "controls".

Availability: Executables, C++ source code and documentation for PedSplit can be downloaded from http://www.pharmacogenetics.ca in the links and software section.


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