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Bioinformatics Advance Access published online on July 9, 2004
Bioinformatics, doi:10.1093/bioinformatics/bth401
Bioinformatics © Oxford University Press 2004; all rights reserved
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Received May 31, 2004
Revised May 31, 2004
Accepted July 1, 2004

Article

DNMAD: web-based diagnosis and normalization for microarray data

Juan M. Vaquerizas 1, Joaquín Dopazo 1, Ramón Díaz-Uriarte 1*

1 Bioinformatics Unit, CNIO, (Spanish National Cancer Centre) Melchor Fernández Almagro 3, 28029 Madrid, Spain

* To whom correspondence should be addressed. E-mail: rdiaz{at}cnio.es.


  Abstract

Summary: We present a web server for Diagnosis and Normalization of MicroArray Data (DNMAD). DNMAD includes several common data transformations such as spatial and global robust local regression, or multiple slide normalization, and allows detecting several kinds of errors that result from the manipulation and the image analysis of the arrays. This tool offers a user-friendly interface, and is completely integrated within the Gene Expression Pattern Analysis Suite (GEPAS).

Availability: The tool is accessible on-line at http://dnmad.bioinfo.cnio.es


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