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Bioinformatics Advance Access published online on October 27, 2004
Bioinformatics, doi:10.1093/bioinformatics/bti088
Bioinformatics © Oxford University Press 2004; all rights reserved
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Received June 17, 2004
Revised September 21, 2004
Accepted October 7, 2004

Applications note

LabArray: real-time imaging and analytical tool for microarrays

Johnson Kian Kok Ng 1 and Wen-Tso Liu 2*

1 Division of Bioengineering, 10 Kent Ridge Crescent, Singapore 119260, Singapore; Environmental Science and Engineering Program, 10 Kent Ridge Crescent, Singapore 119260, Singapore
2 Environmental Science and Engineering Program, 10 Kent Ridge Crescent, Singapore 119260, Singapore; Department of Civil Engineering, 10 Kent Ridge Crescent, Singapore 119260, Singapore

* To whom correspondence should be addressed.
Wen-Tso Liu, E-mail: cveliuwt{at}nus.edu.sg


  Abstract

Summary: Microarrays have been used to perform high-throughput genetic analyses such as single-nucleotide polymorphisms detection and microbial genome analysis. Some of these analyses require real-time monitoring of the hybridisation signals with respect to a varying experimental condition, such as temperature. However, current microarray imaging and analysis packages typically do not possess such real-time capabilities. Therefore, microarray image analyses are often time-consuming and labour-intensive. LabArray was developed to expedite such processes by enabling real-time monitoring of microarray signals.

Availability: LabArray is available at http://www.eng.nus.edu.sg/civil/Labarray/labarray.htm.

Supplementary information: Screenshots and instructions for use are available at the above website.


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