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Bioinformatics Advance Access published online on November 30, 2004
Bioinformatics, doi:10.1093/bioinformatics/bti122
Bioinformatics © Oxford University Press 2004; all rights reserved
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Received August 3, 2004
Revised October 19, 2004
Accepted October 25, 2004

Applications note

MapLinker: a software tool that aids physical map-linked whole genome shotgun assembly

Jian Xu 1 and Jeffrey I. Gordon 1*

1 Center for Genome Sciences and Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, MO 63108 USA

* To whom correspondence should be addressed.
Jeffrey I. Gordon, E-mail: jgordon{at}molecool.wustl.edu


  Abstract

Summary: MapLinker is an analysis tool, as well as a browsing interface, that facilitates integration of whole genome sequence assembly with a clone-based physical map. Using the locations of sequence markers on the physical map, MapLinker generates a tentative sequence map of the genome that serves to verify the map and to guide genome-wide finishing.

Availability: MapLinker is freely available at http://gordonlab.wustl.edu/MapLinker.


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