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Bioinformatics Advance Access published online on November 16, 2004
Bioinformatics, doi:10.1093/bioinformatics/bti146
Bioinformatics © Oxford University Press 2004; all rights reserved
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Received October 20, 2004
Accepted November 8, 2004

Applications note

CyDAS: a cytogenetic data analysis system

Bernhard Hiller 1, Jutta Bradtke 1, Harald Balz 1, and Harald Rieder 2*

1 Institut für Klinische Genetik der Phillipps-Universität Marburg, Bahnhofstr. 7, 35037 Marburg, Germany
2 Institut für Klinische Genetik der Phillipps-Universität Marburg, Bahnhofstr. 7, 35037 Marburg, Germany; Institut für Humangenetik und Anthropologie, Universitätsklinikum Düsseldorf, Universitätsstr. 1, 40225 Düsseldorf, Germany

* To whom correspondence should be addressed.
Harald Rieder, E-mail: info{at}cydas.org


  Abstract

For statistical analyses in cancer cytogenetics, the genomic changes encoded by the karyotype must be translated into numerical codes. We developed a program, which extracts chromosomal gains and losses as well as breakpoints from the karyotype. The changes are compiled in tables according to the chromosome bands involved and/or depicted in projection to the respective chromosome ideogram. The data are ready to be integrated into further statistical analyses. The program may be run as desktop or internet application.

Availability: http://www.cydas.org/.


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