Skip Navigation



Bioinformatics Advance Access published online on November 25, 2004
Bioinformatics, doi:10.1093/bioinformatics/bti157
Bioinformatics © Oxford University Press 2004; all rights reserved
This Article
Right arrow Advance Access manuscript (PDF) Freely available
Right arrow All Versions of this Article:
21/8/1495    most recent
bti157v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Sarkans, U.
Right arrow Articles by Brazma, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sarkans, U.
Right arrow Articles by Brazma, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Received July 2, 2004
Revised October 13, 2004
Accepted November 15, 2004

Article

The ArrayExpress gene expression database: a software engineering and implementation perspective

Ugis Sarkans 1*, Helen Parkinson 1, Gonzalo Garcia Lara 1, Ahmet Oezcimen 1, Anjan Sharma 1, Niran Abeygunawardena 1, Sergio Contrino 1, Ele Holloway 1, Philippe Rocca-Serra 1, Gaurab Mukherjee 1, Mohammadreza Shojatalab 1, Misha Kapushesky 1, Susanna Sansone 1, Anna Farne 1, Tim Rayner 1, and Alvis Brazma 1

1 EMBL Outstation - Hinxton, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom

* To whom correspondence should be addressed.
Ugis Sarkans, E-mail: ugis{at}ebi.ac.uk


  Abstract

Motivation: The lack of microarray data management systems and databases is still one of the major problems faced by many life sciences laboratories. While developing the public repository for microarray data ArrayExpress we had to find novel solutions to many nontrivial software engineering problems. Our experience will be both relevant and useful for most bioinformaticians involved in developing information systems for a wide range of high throughput technologies.

Results: ArrayExpress has been online since February 2002, growing exponentially to well over 10000 hybridizations (as of October 2004). It has been demonstrated that our chosen design and implementation works for databases aimed at storage, access and sharing of high throughput data.

Availability: The ArrayExpress database is available at http://www.ebi.ac.uk/arrayexpress/. The software is open source.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Molecular Cancer TherapeuticsHome page
P. E. Blower, J. S. Verducci, S. Lin, J. Zhou, J.-H. Chung, Z. Dai, C.-G. Liu, W. Reinhold, P. L. Lorenzi, E. P. Kaldjian, et al.
MicroRNA expression profiles for the NCI-60 cancer cell panel
Mol. Cancer Ther., May 1, 2007; 6(5): 1483 - 1491.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.