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Bioinformatics Advance Access published online on November 25, 2004
Bioinformatics, doi:10.1093/bioinformatics/bti161
Bioinformatics © Oxford University Press 2004; all rights reserved
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Received October 7, 2004
Revised November 9, 2004
Accepted November 17, 2004

Applications note

Procom: a web-based tool to compare multiple eukaryotic proteomes

Jin Billy Li 1*, Miao Zhang 2, Susan K. Dutcher 1, and Gary D. Stormo 1

1 Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA
2 Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Biomedical Engineering, Washington University, St. Louis, MO 63130, USA

* To whom correspondence should be addressed.
Jin Billy Li, E-mail: billy{at}ural.wustl.edu


  Abstract

Summary: Each organism has traits that are shared with some, but not all organisms. Identification of genes needed for a particular trait can be accomplished by a comparative genomics approach using three or more organisms. Genes that occur in organisms without the trait are removed from the set of genes in common among organisms with the trait. To facilitate these comparisons, a web-based server, Procom, was developed to identify the subset of genes that may be needed for a trait.

Availability: The Procom program is freely available with documentation and examples at http://ural.wustl.edu/~billy/Procom/.


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