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Bioinformatics Advance Access published online on November 30, 2004
Bioinformatics, doi:10.1093/bioinformatics/bti170
Bioinformatics © Oxford University Press 2004; all rights reserved
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Received December 19, 2003
Revised June 21, 2004
Accepted November 18, 2004

Applications note

BIAS: bioinformatics integrated application software

G. Finak 1, N. Godin 1, M. Hallett 1*, F. Pepin 1, Z. Rajabi 1, V. Srivastava 1, and Z. Tang 1

1 McGill Centre for Bioinformatics, 3775 University St., McGill University, Montreal, Canada, H3A 2B4

* To whom correspondence should be addressed.
M. Hallett, E-mail: hallett{at}mcb.mcgill.ca


  Abstract

Motivation: We introduce a development platform especially tailored to Bioinformatics research and software development. BIAS (Bioinformatics Integrated Application Software) provides the tools necessary for carrying out integrative Bioinformatics research requiring multiple datasets and analysis tools. It follows an object-relational strategy for providing persistent objects, allows third-party tools to be easily incorporated within the system, and supports standards and data-exchange protocols common to Bioinformatics.

Availability: BIAS is an OpenSource project and is freely available to all interested users at http://www.mcb.mcgill.ca/~bias. This web site also contains a paper containing a more detailed description of BIAS and an example implementation of a Bayesian network approach for the simultaneous prediction of gene regulation events and of mRNA expression from combinations of gene regulation events.


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