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Bioinformatics Advance Access published online on February 4, 2005
Bioinformatics, doi:10.1093/bioinformatics/bti306
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© The Author (2005). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org
Received November 24, 2004
Revised January 16, 2005
Accepted January 30, 2005

Applications note

MPSS: an integrated database system for surveying a set of proteins

Pei Hao 1, Wei-Zhong He 2, Yin Huang 3, Liang-Xiao Ma 2, Ying Xu 3, Hong Xi 2, Chuan Wang 3, Bo-Shu Liu 3, Jin-Miao Wang 3, Yi-Xue Li 3, and Yang Zhong 4*

1 School of Life Sciences, Fudan University, Shanghai 200433, China; Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
2 Shanghai Center for Bioinformation Technology, Shanghai 200235, China
3 Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
4 School of Life Sciences, Fudan University, Shanghai 200433, China

* To whom correspondence should be addressed.
Yang Zhong, E-mail: yangzhong{at}fudan.edu.cn


  Abstract

Summary: We design and implement an integrated database system MPSS, which provides a platform to retrieve information about many proteins at a time. This system integrates several important and widely used databases including SwissProt, TrEMBL, PDB and InterPro, plus useful references such as GO and KEGG to other databases. Users may submit a group of protein IDs, entry names, or SwissProt/TrEMBL accession numbers or GenBank GIs through MPSS web interface, and obtain protein annotation information from public databases and pre-computed molecular properties speedily. MPSS can also supply comprehensive information about query proteins, including 3D structures, domains, pathway, gene ontology, and visual presentation of mapping to the GO tree and KEGG pathway, to provide an up-to-date view of available knowledge with regard to the structures and molecular functions of proteins under study.

Availability: MPSS is freely accessible at http://www.scbit.org/mpss/.


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