Bioinformatics Advance Access published online on March 3, 2005
Bioinformatics, doi:10.1093/bioinformatics/bti354
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1 Royal Institute of Technology, AlbaNova University Center, Department of Biotechnology, S-106 91 Stockholm, Sweden
* To whom correspondence should be addressed.
Summary: Forage is an application which uses two neural networks for detecting single nucleotide polymorphisms (SNPs). Potential SNP candidates are identified in multiple alignments. Each candidate is then represented by a vector of features, which is classified as SNP or monomorphic by the networks. A validated data set of SNPs was constructed from experimentally verified SNP data and used for network training and method evalutation. Availability: The package is available at biobase.biotech.kth.se/forage/. Supplementary information: Additional results and method description can be found at biobase.biotech.kth.se/forage/.
Received December 9, 2004
Revised January 13, 2005
Accepted February 23, 2005
Applications note
SNP discovery using advanced algorithms and neural networks
Fredrik Sterky, E-mail: fredrik{at}biotech.kth.se
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