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Bioinformatics Advance Access published online on April 19, 2005
Bioinformatics, doi:10.1093/bioinformatics/bti445
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© The Author (2005). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org
Received February 17, 2005
Revised April 6, 2005
Accepted April 7, 2005

Applications note

Meta-DP: domain prediction meta server

Harpreet Kaur Saini 1 and Daniel Fischer 2*

1 Center of Excellence in Bioinformatics and Computer Science and Engineering, University at Buffalo, 901 Washington St., Suite 300, Buffalo, NY 14203
2 Center of Excellence in Bioinformatics and Computer Science and Engineering, University at Buffalo, 901 Washington St., Suite 300, Buffalo, NY 14203; Bioinformatics/Dept. of Computer Science, Ben Gurion University, Beer-Sheva 84015, Israel

* To whom correspondence should be addressed.
Daniel Fischer, E-mail: dfischer{at}bioinformatics.buffalo.edu


  Abstract

Summary: The Meta-DP domain prediction meta server provides a simple interface to predict domains in a given protein sequence using a number of domain prediction methods. The Meta-DP is a convenient resource because through accessing a single site, users automatically obtain the results of the various domain prediction methods along with a consensus prediction. The Meta-DP is currently coupled to ten domain prediction servers and can be extended to include any number of methods. Meta-DP can thus become a centralized repository of available methods. Meta-DP was also used to evaluate the performance of thirteen domain prediction methods in the context of CAFASP-DP.

Availability: The Meta-DP server is freely available at http://meta-dp.bioinformatics.buffalo and the CAFASP-DP evaluation results are available at http://cafasp4.bioinformatics.buffalo.edu/dp/update.html.


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