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Bioinformatics Advance Access published online on July 14, 2005

Bioinformatics, doi:10.1093/bioinformatics/bti584
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© The Author (2005). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org
Received May 13, 2005
Revised July 8, 2005
Accepted July 13, 2005

Applications note

simuPOP: a forward-time population genetics simulation environment

Bo Peng 1* and Marek Kimmel 1

1 Department of Statistics, Rice University 6100 Main St. MS138 Houston, TX, 77005

* To whom correspondence should be addressed.
Bo Peng, E-mail: bpeng{at}rice.edu


   Abstract

Summary: simuPOP is a forward-time population genetics simulation environment. The core of simuPOP is a scripting language (Python) that provides a large number of objects and functions to manipulate populations, and a mechanism to evolve populations forward in time. Using this R/Splus-like environment, users can create, manipulate and evolve populations interactively, or write a script and run it as a batch file. Due to its flexible and extensible design, simuPOP can simulate large and complex evolutionary processes with ease. At a more user-friendly level, simuPOP provides an increasing number of built-in scripts that perform simulations ranging from basic population genetics models to generating datasets under complex evolutionary scenarios.

Availability: simuPOP is freely available at http://www.stat.rice.edu/~bpeng/simuPOP.htm, distributed under GPL license.


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