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Bioinformatics Advance Access published online on August 4, 2005
Bioinformatics, doi:10.1093/bioinformatics/bti610
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© The Author (2005). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org
Received June 27, 2005
Revised July 28, 2005
Accepted July 29, 2005

Applications note

Blast2GO: a universal tool for annotation and visualization in functional genomics research

Ana Conesa 1* *, Stefan Götz 2 *, Juan Miguel García-Gómez 2, Javier Terol 1, Manuel Talón 1, and Montserrat Robles 2

1 Centro de Genómica, Instituto Valenciano de Investigaciones Agrarias, Moncada, Valencia, Spain
2 BET-ITACA, Universidad Politécnica de Valencia, Valencia, Valencia, Spain

* To whom correspondence should be addressed.
Ana Conesa, E-mail: aconesa{at}ivia.es


  Abstract

Summary: We present here BLAST2GO (B2G), a research tool designed with the main purpose of enabling Gene Ontology (GO) based data mining on sequence data for which no GO annotation is yet available. B2G joints in one application GO annotation based on similarity searches with statistical analysis and highlighted visualization on directed acyclic graphs (DAG). This tool offers a suitable platform for functional genomics research in non-model species. B2G is an intuitive and interactive desktop application which allows monitoring and comprehending the whole annotation and analysis process.

Availability: Blast2GO is freely available via Java Web Start at http://www.blast2go.de.

Supplementary material: http://www.blast2go.de -> Evaluation.

*These authors contributed equally to this work.
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