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Bioinformatics Advance Access published online on August 25, 2005
Bioinformatics, doi:10.1093/bioinformatics/bti643
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© The Author (2005). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org
Received May 31, 2005
Revised August 18, 2005
Accepted August 22, 2005

Applications note

PAWE-3D: visualizing Power for Association With Error in case/control genetic studies of complex traits

Derek Gordon 1*, Chad Haynes 1, Jon Blumenfeld 2, and Stephen J. Finch 3

1 Laboratory of Statistical Genetics, Rockefeller University, 1230 York Avenue, New York, NY 10021 USA
2 The Rogosin Institute, 505 East 70th Street, New York, NY 10021 USA; Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021 USA
3 Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, NY 11794 USA

* To whom correspondence should be addressed.
Derek Gordon, E-mail: pawe3d{at}linkage.rockefeller.edu


  Abstract

A website that plots power and sample size calculations over a range of up to eight parameters (including diagnostic misclassification error parameters) for two commonly used statistical tests of genetic association, the linear trend test and the genotypic test of association.

Availability: This method is made available via the website http://linkage.rockefeller.edu/pawe3d/.


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