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Bioinformatics Advance Access published online on August 30, 2005
Bioinformatics, doi:10.1093/bioinformatics/bti649
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© The Author (2005). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org
Received July 13, 2005
Revised August 24, 2005
Accepted August 25, 2005

Applications note

HAPLOT: a graphical comparison of haplotype blocks, tagSNP sets and SNP variation for multiple populations

Sheng Gu 1*, Andrew J. Pakstis 1, and Kenneth K. Kidd 1

1 Department of Genetics, Yale University School of Medicine, New Haven, USA

* To whom correspondence should be addressed.
Sheng Gu, E-mail: sheng.gu{at}yale.edu


  Abstract

Summary: Understanding of human variation relevant to association studies can benefit from population comparison, especially comparing populations in the same geographical region. Variations in LD patterns, in tagSNP sets, and in SNP heterozygosities among populations can be used to infer the evolutionary pattern. We present here a win32 system based Perl/Tk application for visual comparisons of these variations in different populations.

Availability: The application package is available at http://info.med.yale.edu/genetics/kkidd/programs.html.


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