Bioinformatics Advance Access published online on October 6, 2005
Bioinformatics, doi:10.1093/bioinformatics/bti705
1 DBBM, Instituto Oswaldo Cruz, Fiocruz, Brazil
* To whom correspondence should be addressed.
Summary: The growth of genome data and analysis possibilities have brought new levels of difficulty for scientists to understand, integrate and deal with all this ever-increasing information. In this scenario, GARSA has been conceived aiming to facilitate the tasks of integrating, analyzing and presenting genomic information from several Bioinformatics tools and Genomic databases, in a flexible way. GARSA is a user-friendly web-based system designed to analyze genomic data in the context of a pipeline. EST and GGS data can be analysed using the system since it accepts: a) chromatograms, b) download of sequences from GenBank, c) Fasta files stored locally or d) a combination of all 3. Quality evaluation of chromatograms, vector removing and clusterization are easily performed as part of the pipeline. A number of local and customizable Blast and CDD analyses can be performed as well as Interpro, complemented with phylogeny analyses. GARSA is being used for the analyses of Trypanosoma vivax (GSS and EST), T. rangeli (GSS, EST and ORESTES), Bothrops jararaca (EST), Piaractus mesopotamicus (EST) and Lutzomyia longipalpis (EST). Availability: The GARSA system is freely available under GPL license1. For download requests visit http://www.biowebdb.org/garsa/ or contact Dr. Alberto Dávila.
Received July 10, 2005
Revised September 7, 2005
Accepted October 5, 2005
Applications note
GARSA: Genomic Analysis Resources for Sequence Annotation
2 Lab. de Bioinformática & Lab. de Protozoologia - MIP/CCB, Universidade Federal de Santa Catarina, Brazil
3 Departamento de Ciência da Computação/Núcleo de Computação Eletrônica - UFRJ, Brazil
4 Engenharia de Bioprocessos e Biotecnologia, Universidade Federal do Paraná, Brazil
5 Instituto Militar de Engenharia, Brazil
Alberto M. R. Dávila, E-mail: davila{at}fiocruz.br
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Abstract
1 http://www.biowebdb.org/garsa/
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