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Bioinformatics Advance Access published online on October 25, 2005

Bioinformatics, doi:10.1093/bioinformatics/bti725
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© The Author (2005). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received August 11, 2005
Revised October 12, 2005
Accepted October 17, 2005

Applications note

GSMA: software for analysis of the genome-search meta-analysis method

Fabio Pardi 1, Douglas F. Levinson 2, and Cathryn M. Lewis 1*

1 Department of Medical and Molecular Genetics, King's College London, 8th Floor Guy's Tower, Guy's Hospital, London SE1 9RT, United Kingdom
2 Division of Clinical Neurobiology and Behavior, University of Pennsylvania School of Medicine, 3535 Market St., Rm 4006, Philadelphia, PA 19104-3309, USA

* To whom correspondence should be addressed.
Cathryn M. Lewis, E-mail: Cathryn.lewis{at}genetics.kcl.ac.uk


   Abstract

Meta-analysis can be used to pool results of genome-wide linkage scans. This is of great value in complex diseases, where replication of linked regions occurs infrequently. The Genome Search Meta-Analysis method is widely used for this analysis, and a computer program is now available to implement the GSMA.

Availability: http://www.kcl.ac.uk/depsta/memoge/gsma/.


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