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Bioinformatics Advance Access published online on November 2, 2005

Bioinformatics, doi:10.1093/bioinformatics/bti744
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© The Author (2005). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received August 2, 2005
Revised October 7, 2005
Accepted October 24, 2005

Applications note

mILD: a tool for constructing and analyzing matrices of pairwise phylogenetic character incongruence tests

Paul J. Planet 1 and Indra Neil Sarkar 2*

1 Divisions of Invertebrate Zoology, American Museum of Natural History, New York, NY USA
2 Divisions of Invertebrate Zoology, American Museum of Natural History, New York, NY USA; Library Services, American Museum of Natural History, New York, NY USA

* To whom correspondence should be addressed.
Indra Neil Sarkar, E-mail: sarkar{at}amnh.org


   Abstract

Summary: Pairwise comparisons of disagreement in phylogenetic datasets offer a powerful tool for isolating historical incongruence for closer analysis. Statistically significant phylogenetic character incongruence may reflect important differences in evolutionary history, such as horizontal gene transfer. Such testing can also be used to specify possible combinations of datasets for further phylogenetic analysis. The process of comparing multiple datasets can be very time consuming, and it is sometimes unclear how to combine data partitions given the observed patterns of incongruence. Here we present an application that automates the process of making pairwise comparisons between large numbers of phylogenetic datasets using the Incongruence Length Difference (ILD) test. The application also implements strategies for data combination based on the patterns of incongruence observed in pairwise comparisons.

Availability: The application is freely available as a Perl script that interacts with the command-line version of PAUP*.

Supplementary Information: http://www.GenomeCurator.org/mILD/.


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D. L. J. Quicke, O. R. Jones, and D. R. Epstein
Correcting the Problem of False Incongruence Due to Noise Imbalance in the Incongruence Length Difference (ILD) Test
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[Abstract] [Full Text] [PDF]



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