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Bioinformatics Advance Access published online on May 8, 2006
Bioinformatics, doi:10.1093/bioinformatics/btl179
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© The Author (2006). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Received February 17, 2006
Revised April 19, 2006
Accepted May 3, 2006

Applications note

HoSeqI: automated homologous sequence identification in gene family databases

Anne-Muriel Arigon 1 *, Guy Perrière 1, and Manolo Gouy 1

1 Laboratoire de Biométrie et Biologie Évolutive, UMR CNRS 5558, Université Claude-Bernard Lyon 1, 43 bd. du 11 Novembre 1918, 69622 Villeurbanne Cedex, France

* To whom correspondence should be addressed.
Anne-Muriel Arigon, E-mail: arigon{at}biomserv.univ-lyon1.fr


  Abstract

Summary: We present a web service allowing to automatically assign sequences to homologous gene families from a set of databases. After identification of the most similar gene family to the query sequence, this sequence is added to the whole alignment, and the phylogenetic tree of the family is rebuilt. Thus, the phylogenetic position of the query sequence in its gene family can be easily identified.

Availability: http://pbil.univ-lyon1.fr/software/HoSeqI/.

Supplementary Information: Supplementary materials are available at Bioinformatics online.

Associate Editor: Joaquin Dopazo
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